Evidence-Based Outcomes

 
Patella tendon PRP injection.jpg
 

General

  • Malanga G, Ibrahim V. Scientific evidence of platelet-rich plasma for orthopedic conditions: basic science to clinical research and applications. Regenerative Treatments in Sports Medicine and Orthopedics. 2018. Chapter 7. 89-117.


Post-PRP Rehabilitation

  • Mautner K, Malanga G, Colberg R. Optimization of ingredients, procedures, and rehabilitation for platelet-rich plasma injections for chronic tendinopathy. Pain Manag. 2011. 1(6):523-532.


Knee osteoarthritis

  • Dai WL, Zhou AG, Zhang H, Zhang J. Efficacy of platelet-rich plasma in the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials. Arthroscopy. 2017 33(3): 659-670.

  • Riboh JC, Saltzman BM, Yanke AB, Fortier L, Cole BJ. Effect of leukocyte concentration on the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis. AJSM. 2016; 44(3): 792-800.

  • Lana JFSD et al. Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee. JSRM. 2016. Vol 12 No 2.


Lateral epicondylosis (“tennis elbow”)

  • Peerbooms JC, Sluimer J, Brujin DJ, Gosens T. Positive effects of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. AJSM. 2010; 38(2):255-262.

  • Mishra A, Nebojsa VS, Edwards S, Jones G, Sampson S, Vermillion DA, Ramsey ML, Karli DC, Rettig AC. Efficacy of platelet-rich plasma for chronic tennis elbow: a double-blind, prospective, multi-center, randomized controlled trial of 230 patients.


Patella tendinopathy (“jumper’s knee”)

  • Filardo G, Kon E, Della Villa S, Vincentelli F, Fornasari P, Maracacci M. Use of platelet-rich plasma for the treatment of refractory jumper’s knee. Int Orthop. 2010;34:909-915.

  • Dragoo JL, Wasterlain AS, Braun HJ, Nead KT. Platlet-rich plasma as a treatment of patellar tendinopathy: a double-blind, randomized controlled trial. AJSM. 2014; 42(3):610-618.


Gluteal tendinopathy (“Greater trochanteric pain syndrome”)

  • Fitzpatrick J, Bulsara MK, O’Donnell J, McCrory PR, Zheng MH. The effectiveness of platelet-rich plasma injections in gluteal tendinopathy: a randomized, double-blind controlled trial comparing a single platelet-rich plasma injection with a single corticosteroid injection. AJSM. 2018; 46(4):933-939.


Hamstring tendinopathy

  • A Hamid MS, Mohammed Ali MR, Yusof A, George J, Lee LP. Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial. AJSM. 2014; 42(10):2410-2418.


Achilles tendinopathy

  • Ferrero G, Fabbro E, Orlandi D, Martini C, Lacelli F, Serafini G, Silvestri E, Sconfienza LM. Ultrasound-guided injection of platelet-rich plasma in chronic Achilles and patellar tendinopathy. J Ultrasound. 2012; 15(4): 260-266.

  • Murawski CD, Smyth NA, Newman H, Kennedy JG. A single platelet-rich plasma injection for chronic midsubstance Achilles tendinopathy: a retrospective preliminary analysis. Foot Ankle Spec. 2014; 7(5): 372-376.

  • Filardo G, Kon E, DiMatteo B, DiMartino A, Tesei G, Pelotti P, Cenacchi A, Marcacci M. Platelet-rich plasma injections for the treatment of refractory Achilles tendinopathy: results at 4 years. Blood Transfus. 2014; 12(4): 533-540.


Rotator cuff tendinopathy 

  • Rha DW, Park GY, Kim YK, Kim MT, Lee SC. Comparison of the therapeutic effects of ultrasound-guided platelet-rich plasma injection and dry needling in rotator cuff disease: a randomized controlled trial. Clin Rehabil. 2013. 27(2): 113-122.

  • Lee HW, Choi KH, Kim JY, Yang I, Noh KC. Prospective clinical research of the efficacy of platelet-rich plasma in the outpatient-based treatment of rotator cuff tendinopathy. Clin in Shoulder and Elbow. 2019; 22(2): 61-69.


Hip labrum tear

  • DeLuigi AJ, Blatz D, Karam C, Gustin Z, Gordon AH. Use of platelet-rich plasma for the treatment of acetabular labral tear of the hip: a pilot study. Am J Phys Med Rehabil. 2019; 98(11):1010-1017.


Plantar fasciitis

  • Yang W, Han YH, Cao XW, Pan J, Zeng L, Lin J, Liu J. Platelet-rich plasma as a treatment for plantar fasciitis: a meta-analysis of randomized controlled trials. Medicine. 2017; 96(44).

  • Mahindra P, Yamin M, Selhi HS. Chronic plantar fasciitis: effect of platelet-rich plasma, corticosteroid, and placebo. Orthopedics. 2016; 39(2):285-289.